
SIGNS AND SYMPTOMS:
The initial symptoms of mesothelioma usually occur months prior to diagnosis in the form of chest
pain (non-pleuritic, as a prick, but dull and
poorly localized), as wellas Dyspnea (shortness of breath sensation) variable in
relation to the quantity of pleural effusion.
Dry cough, fever and night sweats, asthenia (fatigue) and weight loss can also appear. Occurs most often in a unilateral way (95%), and especially in the area of the righthemithorax (60%), probably in
relation to its greater volume.
The progression of the disease produces shortness of
breath, and the invasion of neighbouring structures can lead to dysphagia (difficulty swallowing), dysphonia, brachial plexopathy (involvement of the
nervous
Plexus), or superior vena cava syndrome (when there
is compression of the main vein is produce symptoms such
as dyspnea, swelling on the face and arm, cough, chest pain, dysphagia, cyanosis,
congestionheadache and dizziness).
Mesothelioma can also be accompanied by symptoms of Paraneoplastic syndromes(it's different groups of symptoms suffered by cancer patients, and that cannot be explained by the local tumor invasion or its metastases, they are associated with the release of biologically active substances by the tumor, that exert their effects at a
distance. In fact, may be the first sign that warn of the presence of a tumor).